Characteristics of patients with a lipoprotein(a) assessment – a health insurance claims database analysis

Abstract Background Elevated lipoprotein(a) [Lp(a)] has been established as marker of cardiovascular [CV] risk, however, it is not commonly assessed. Purpose The aim the study was to characterize patients who underwent their first Lp(a) testing regarding sociodemographic characteristics and clinical outcomes. Methods A retrospective analysis performed on data from 4 million individual in a local database that provides complete, longitudinal, anonymized claims data. are representative German population terms age gender. billing codes documented ambulatory setting were used identify adult 2015 2018 (index quarter defined test respective year). These must have had any year prior index quarter. Patient needed be available for at least 1 before after or until death, whichever came first. Patients followed maximum four years. Results Within four-year period, 36.609 (0.83% set) an test, whom majority (58%) women. 50% women (median 49 years) 32% men 56 younger than 50 most prevalent comorbidities (based International Classification Diseases, version 10, modification) were: dyslipidemia (E78) 46%, essential hypertension (I10) dorsalgia (M54) 25%, overweight/obesity (E66) 18%, chronic ischemic heart disease (I25) 16%, type 2 diabetes mellitus (E11) 15%, other coagulation defects (D68) 14%, depressive episodes (F32) 14%; disorders refraction accommodation (H52) 13%, somatoform (F45) non-toxic goiter (E04) hypothyroidism (E03) kidney (N18) 11%. rates events procedures listed table below. Conclusions tests rarely Germany. Women more often tested men, this done age. suggest CV events/ hospitalizations frequently trigger assessment. displayed high prevalence comorbidities. opportunity better risk by once lifetime independent recommended current European Society Cardiology/European Atherosclerosis guidelines. FUNDunding Acknowledgement Type funding sources: Private company. Main source(s): funded Novartis Pharma GmbH, Nuremberg.